Implantable Intrathecal Pump

It is useful for chemical neuromodulation of central nervous system to significantly reduce perception of pain by delivery of the drug. In simple terms, it is a completely internalized system comprising of an intrathecal catheter which is introduced in the fluid containing space around the spinal cord and connected to a drug reservoir sited in a pocket made under the skin. This facilitates administration of a drug directly on the target pain receptors present in spinal cord responsible for pain transmission. The intrathecal administration permits the drug to bypass enteric absorption and/or blood brain barrier hence the dose required is a fraction of systemic dose with improved efficacy and minimized side-effects. For example, dose of morphine from oral to intrathecal route decreases from approximately 300mg to 1mg. The continuous drug delivery ensures a steady drug level in blood, improving quality of analgesia and a miniscule dose required for this purpose also